From "Mork & Mindy: In Mork We Trust (#1.21)" (1979)
Orson: The report, Mork.
Mork: This week I discovered a terrible disease called loneliness.
Orson: Do many people on Earth suffer from this disease?
Mork: Oh yes sir, and how they suffer. One man I know suffers so much he has to take a medication called bourbon, even that doesn't help very much because then he can hear paint dry.
Orson: Does bed rest help?
Mork: No because I've heard that sleeping alone is part of the problem. You see, Orson, loneliness is a disease of the spirit. People who have it think that no one cares about them.
Orson: Do you have any idea why?
Mork: Yes sir you can count on me. You see, when children are young, they're told not to talk to strangers. When they go to school, they're told not to talk to the person next to them. Finally when they're very old, they're told not to talk to themselves, who's left?
Orson: Are you saying Earthlings make each other lonely?
Mork: No sir I'm saying just the opposite. They make themeslves lonely, they're so busy looking out for number one that there's not enough room for two.
Orson: It's too bad everybody down there can't get together and find a cure.
Mork: Here's the paradox sir because if they did get together, they wouldn't need one.